This is old, but I'm late getting there, so... It's a good illustration of how large cross-species datasets, good questions, and computational power can help answer questions in genetics. It's all about narrowing down your search, from motivated assumptions. Easy to read version here:
SetTheory With Databases on Corante's Living Code. Citation to still easy but more bio article here:
bio.com's Gene Maps of Simpler Lifeforms...
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